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BPT
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Research
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Research topics
Novel biocatalyst
In the presence of cytosolic DNA, the enzyme cyclic GMP-AMP synthase (cGAS) catalyzes the synthesis of the second messenger 2'3'-cyclic GMP-AMP (cGAMP) [1]. The cyclic dinucleotide cGAMP is currently of [...] discovery: past, present, and future. Journal of Industrial Microbiology & Biotechnology, 43(2-3), pp.155-176. [2] Zarins-Tutt, J., Barberi, T., Gao, H., Mearns-Spragg, A., Zhang, L., Newman, D. and Goss [...] [1] Sun, L., et al, Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science (New York, N.Y.), 2013. 339(6121): p. 786-791. [2] Corrales, L., et al, Direct …